Abraman Zucker
- 1930 – New York’s 4th congressional district (S) – lost
Martin Zucker
- 1996 – California’s 27th congressional district (NL) – lost
Michael Zumbluskas
- 2022 – New York’s 12th congressional district (R) – lost
Elmo Russell Zumwalt, Jr.
- 1976 – United States Senate (Virginia) (D) – lost
Tricia Zunker
- 2020 – Wisconsin’s 7th congressional district (Special) (D) – lost
- 2020 – Wisconsin’s 7th congressional district (D) – lost
Lawrence Zupan
- 2018 – United States Senate (Vermont) (R) – lost
Jim Zupancic
- 2004 – Oregon’s 5th congressional district (R) – lost
Harold Zupp
- 1956 – Minnesota’s 2nd congressional district (DFL) – lost
Aaron Zurbrugg
- 2012 – Ohio’s 14th congressional district (I-W/I) – lost
Kenneth Zurbrugg
- 1976 – Ohio’s 19th congressional district (I) – lost
Kathy Jo Zurek
- 2010 – United States Senate (Alaska) (W/I) – lost
William P. Zurick
- 1970 – Pennsylvania’s 17th congressional district (D) – lost
Theodore ‘Ted’ Zuur
- 1986 – California’s 5th congressional district (PF) – lost
- 1987 – California’s 5th congressional district (Special) (PF) – lost
- 1988 – California’s 5th congressional district (PF) – lost
John Matthew Zwach, Sr.
- 1966 – Minnesota’s 6th congressional district (R) – won
- 1968 – Minnesota’s 6th congressional district (R) – won
- 1970 – Minnesota’s 6th congressional district (R) – won
- 1972 – Minnesota’s 6th congressional district (R) – won
Erin R. Zweigart
- 2004 – Illinois’ 12th congressional district (R) – lost
Donald J. Zwick
- 1980 – Ohio’s 1st congressional district (D) – lost
Tamara Zwinak
- 2020 – North Carolina’s 11th congressional district (G) – lost
